MAXIMUM SPEED AND RELIABILITY

The Zoom HT microplate washer is a robust and easy-to-use system that delivers the speed you need for high throughput plate washing. The unmatched speed of the system is the result of the integrated stackers and a one-rail design. This plate washer can process both 96 and 384 well microplates without changing the wash head.

The fastest plate washer on the market today

It takes only 17 seconds for a triple wash of a 96 well microplate. Combined with the unique one-rail plate transfer design which moves the plate a very short distance from the stack to the wash position. This enables a typical throughput of 150 washed plates per hour, or up to 1050 plates per day (3 x 300 µL, 7 h per day, 1 single  Zoom HT).

A single wash head for all plate types

Each wash channel has its own aspirate and dispense tip, which allows simultaneous washing of all 96 wells. The same 96 channel wash head is used for 384 well washing in four quadrants, making it unnecessary to purchase different wash heads for different plate types.  Rapid positioning of the wash head provides 384 well wash speeds comparable to 384 well channel washers. Large diameter aspirate tips, 3-dimensional (3D) tip positioning and a constant flow rate vacuum pump ensure a smooth and efficient washing experience.

Individual configuration of the washing protocol 

Two wash modes are available: Regular wash mode and Superwash mode (also known as “Overflow mode”). When using the regular wash mode, the wash fluid that is dispensing and evacuated follow each other. When using the Superwash mode, the wash fluid that is dispensing and evacuated are conducted simultaneously creating a continuous wash fluid flow throughout the entire well.  The Zoom HT supports creating and storing of the 3D tip positioning profile for each plate type and assay. This profile defines the aspirate tip horizontal and vertical positions thereby mapping how the well is aspirated. In addition, the speed with which the tip is immersed into the well is adjustable. Fine-tuning of all the parameters of the wash procedure will allow to wash even loosely adherent cultured cells. The Zoom HT will have residual wash fluid volumes of less than 1 μL/well, this can be achieved when a surfactant is present in the wash fluid.

A unique self-emptying liquid discharge system

The discarded wash fluids are captured by a self-emptying waste trap, which allows uninterrupted processing of large plate batches. Biohazard waste management is supported by the automatic addition of a decontamination solution which is continuously drained from the trap.

Automatic switch of buffer liquids

The Zoom HT is available in 3 different configurations using a one, two or four wash buffer inlet. This is advantageous for applications that require sequential cleaning with different buffers or for an automatic cleaning routine after using the system.

Easy maintenance

The unique design of the dispense manifold eliminates the need for any special cleaning. The aspirate head is maintenance free because of the large aspirate tip diameter. This is  combined with a continuous vacuum that reliably prevents any accumulation of reagent residue.

Optional Dispense Module

The optional Dispense Module is an easy-to-install plug-and-play device, is extremely easy to use and requires no calibration. With the addition of a dispense module the Zoom HT Washer becomes an efficient washer-dispenser combination system. The Dispensing Module provides single or dual-channel dispensing of reagents using direct drive and positive displacement syringes to ensure the highest precision and accuracy when dispensing. The dispense module feeds one or two 8- or 16-way manifolds for 96 and/or 384 well microplates

TECHNICAL DETAILS (ZOOM HT WASHER)

Wash head: 96 channel wash head for fast processing of 96 and 384 well microplates
Wash modes: Standard and Superwash
Wash fluid selection: 1, 2 or 4 inlet versions
Wash volume: 5-300 µL
Aspirate tip descent speeds: Slow, Medium, Fast
Soak time: 0-99 s
Shaking: Up to 80 s, amplitude 1 mm, frequency 12 Hz
Number of programs: Up to 99
Wash cycles per program: Up to 99

X-CLARITY II Tissue Clearing System

Features

Easy installation, Ultrafast clearing, Reliable results

The new X-CLARITY II Tissue Clearing System from the imaging specialists at Logos Biosystems provides an all-in-one solution for electrophoretic tissue clearing. The groundbreaking CLARITY™ method developed by the Deisseroth Lab at Stanford University (Chung et al, Nature 497:332-337) provides unparalleled tissue samples for imaging. Combining an innovative electrode design and an integrated cooling system, the X-CLARITY™ Tissue Clearing System allows for faster and more consistent tissue clearing.

Many researchers currently attempting the CLARITY™ method often encounter difficulties that range from instrument construction to poor clarifying, resulting in the loss of valuable samples. Days or even weeks spent processing a precious sample can end in frustration and disappointment.

The X-CLARITY™ Tissue Clearing System greatly simplifies the CLARITY™ process, can clarify a whole adult mouse brain in under  48 hours, and dramatically increases your chances of obtaining transparent tissue samples for use in downstream labeling.

HOW IT WORKS ?

Typical negative effects related with conventional electrophoretic tissue clearing methods include burning, melting, the formation of black precipitates, and bubble trapping. The main causes of these artifacts are due to irregular electric currents and poor temperature control during electrophoresis. The X-CLARITY™ dramatically reduces the negative effects associated with standard electrophoretic  tissue clearing with a unique electrode design and an active cooling system. The X-CLARITY™ Tissue Clearing System is composed of  four components: 1) the X-CLARITY™ ETC Controller, 2) X-CLARITY™ ETC Chamber 3) X-CLARITY™ pump and 4) X-CLARITY™ buffer reservoir.  The X-CLARITY™ ETC Controller works as both a power supply and temperature controller. At the heart of the X-CLARITY™ Tissue Clearing System is the X-CLARITY™ ETC Chamber. A tissue sample is placed inside the X-CLARITY™ ETC Chamber where it undergoes electrophoresis  to remove lipids. Clearing buffer is continually circulated through the chamber under temperature controlled conditions, minimizing the probability of artifacts arising due to poor temperature control.

Highlights

• Exceptional transparency
• Fastest processing time
• Easy installation and operation
• Minimized artifacts
• No leaking, no boiling
• Pre-optimized protocol

ACCELERATE YOUR RESEARCH WITH THE X-CLARITY™ TISSUE CLEARING SYSTEM

Compared to other methods, the X-CLARITY™ Tissue Clearing System dramatically reduces tissue clearing time. A whole adult mouse brain can be cleared in under 48 hours. Depending on the thickness, mouse brain slices may be cleared much faster. Additionally, the speed of  the X-CLARITY™ Tissue Clearing System makes optimizing for other organs and tissues a much easier endeavor.

One of the most exciting features of the CLARITY™ technology is that, it allows for the penetration of and labeling with macromolecules  such as antibodies or oligonucleotides, generating unprecedented 3D images that show the relationship between structure and function.  Chemical tissue clearing technologies introduced in recent years generally do not accommodate labeling with macromolecules. CLARITY™ overcomes this limitation and even enables multiple rounds of antibody labeling. The X-CLARITY™ Tissue Clearing System also successfully produces samples that demonstrate the efficient penetration of antibodies.

WHAT IS CLARITY™ ?

CLARITY™ is a novel technology that produces a transparent tissues by forming a hydrogel network that supports the ultrastructure while allowing for the removal of lipids. Unlike other tissue clearing methods, the CLARITY™ uniquely enables the efficient labeling  of tissues with macromolecules such as antibodies and nucleic acids, making high resolution imaging possible. CLARITY™ is expected  to overcome the current limitation of light microscopy technology, which does not allow the imaging of tissues without first creating  slices. CLARITY™ is the trademark of Stanford University.

SIMPLICITY AND SENSITIVITY FOR ALL LEVELS OF EXPERIENCE

The Tristar 3 is a user-friendly and affordable filter-based multimode plate reader that offers the high-performance analysis you expect from Berthold Technologies instruments. Equipped with ONE-4-ALL optics for uncompromised performance of all detection modes, the system is ready to perform absorbance, luminescence and fluorescence measurements. It provides you with the flexibility for today, tomorrow, and beyond to master your changing plate reading applications:

• High-sensitivity Luminescence
• BRET
• Absorbance (UV/VIS)
• Fluorescence
• FRET

Broad wavelength range selection from UV through the visible range

From UV absorbance for DNA quantification to measurements in the far red or NIR, the Tristar 3 is ready for any assay and greatly improves the wavelength range of the TriStar².

BRET/BRET2 and NanoBRET™ upgradable

All Tristar 3 preconfigured models have the features you need to perform BRET assays: best-in-class luminescence sensitivity and a high quality filters. To start working with BRET, just order the correct filters for BRET1, BRET2, and NanoBRET™.

ONE-4-ALL Optics for uncompromised performance

Berthold Technollogies’ patented ONE-4-ALL optics have been optimized to combine the stability and user-friendliness of a multimodal optical system with the sensitivity and versatility of a dedicated optical devices.

ONE-4-ALL optics work with both filter and monochromator based applications, so there is never a compromise in performance in any mode.

High-performance filter system – when sensitivity counts

The quick-change filter technology of the Tristar series provides you with the flexibility required to meet your application needs. With your choice of up to 40 different excitation and emission filters can be easily mounted on exchangeable filter slides.

The filters are characterized by high transmittance properties which can be up to 25-fold more sensitive than monochromators. Technologies like Time-Resolved Fluorescence is measured more efficiently with filters.

Furthermore, filters with a large bandwidth are available to analyze fluorophores with wide spectra and all luminescence-based assays requiring the use of filters, e.g. BRET, BRET2 and NanoBRET™ assays.

Ergonomic design to support your work

The ergonomic design of the system provides full frontal access for all key operations (e.g. plate loading, filter change and connecting reagents). Reagent vials can be stored in the integrated front compartment providing easy access and visibility. The Tristar 3 contains a removable trough that can be filled with water or ice to keep all of your temperature sensitive reagents cooled. Different reagent tube holders are available to ensure secure handling of valuable reagents. The system has a flat surface on top, providing enough space for a laptop.

Powerful crosstalk control – reliable results

Do you often see a few high-intensity samples surrounded by wells of low-intensity when running your samples?  Then you are potentially affected by a phenomenon called crosstalk, this can produce wrong results and wrong conclusions. The crosstalk reduction design of the Tristar 3 almost eliminates this problem: with a crosstalk of 10^-6, you will never have to worry about the position of your high-intensity samples in your plate.

JET injectors: highest accuracy, speed and cell-friendliness

The Tristar 3 can be equipped with up to 3 JET injectors with variable volumes in pre-measurement or measurement position. The ultra-fast injection speed of JET injectors eliminates any delay between injection and measurement. This enables the Tristar 3 to measure ultra fast reactions, e.g. flash luminescence.

Berthold Technologies JET injectors use Teflon bellows for accurate and fast injections. This guarantees the most efficient mixing as well as extreme longevity.

• Highest accuracy and reproducibility with greater than 98 % accuracy and reproducibility over the entire volume range.
• Low reagent consumption due to the low dead volume and the injectors can recover up to 60 % of the reagent in the injector line. A single priming sequence is enough to achieve a 99 % homogeneous mix at the tip.
• Low maintenance costs – friction-free operation enables more than 3 million injections without mechanical failure.
• Optimal performance in flash-kinetics – ultra-fast injection enables the measurement of the first 150 ms of a kinetic assay (e.g. Fura-2 or Acridinium ester assays).
• Worry-free injection of cell suspensions – negligible shear forces are ideal when working with living cells, e.g. in Aequorin-based calcium assays.

Convenient Software options

Our microplate readers are powered by LightCompass®, a flexible software enabling easy data acquisition, analysis and reporting using Berthold Technologies’ instruments. It has been optimized for different microplate and tube formats. LightCompass® features all the functions you can expect from an advanced scientific software, such as flexible creation of measurement protocols, curve fitting, qualitative analysis and compliance with FDA 21 CFR Part 11.

LightCompass® is available in 3 different versions: Basic, Plus and Professional. Just pick the version that better suits your research needs.

For many laboratories ensuring compliance with a number of GMP and GLP requirements is essential. We provide a number of tools and services to help you ensure that your system is running at peak performance.

Validation Tools

We provide a variety of tools to help you check and confirm the performance of your products over time.

Service

Berthold Technologies provides a team of dedicated factory-trained service engineers and experts to optimize your productivity. We and our local partners are always at your disposal.

Support

Our team of technical support scientists is your resource to overcome the unique challenges your application brings. Contact our team to discuss your assay, experiment design, data analysis, troubleshooting questions.

NuGenius is a new generation, low cost, integrated imaging system for DNA and protein analysis and gel documentation.

Complete gel documentation workstation

NuGenius is the ultimate in compact gel documentation workstations. Using a choice of UV, blue or white lighting options you can capture and edit images of fluorescent ethidium bromide, SYBR^® Safe or GelGreen^TM DNA gels and protein gels stained with Coomassie Blue at the workstation. You can even capture stain-free gel images using a NuGenius+ which is specially optimised for this application.

For an entry level system, the NuGenius comes with a ground breaking 5 million pixel CCD camera giving superb pixel resolution and unrivalled sensitivity. NuGenius offers a maximum viewing area of 20 x 24cm which is very large for such a small, compact unit.

NuGenius+ has been designed for stain free applications. NuGenius+ can be automatically set up in seconds to capture great images of TGX Stain-Free™ FastCast™ acrylamide gels, Mini-PROTEAN^® and Criterion™ TGX Stain-Free™ precast gels. Utilising this cost-effective system for imaging stain-free gels will save researchers hours of staining preparation time.

Features

Gel imaging at a touch. DNA and protein gel imaging your way!

• Compact workstation
  Plenty of bench space for your research
• Complete with built-in processor, touch screen and NuGenius software
  Easily capture and edit images on screen without a computer
• Motor driven zoom lens
  Automatic set up for easy image capture
• 5m pixel camera
  Resolves close bands and detects nanogram amounts
• White, UV and blue lighting options
  Flexibility to image fluorescent and visibly stained gels
• Stain-free imaging capability with the NuGenius+
  Capture images of TGX Stain-Free™ FastCast™ acrylamide gels and many more
• Complete networking connectivity (optional)
  Easily share and store your results
• GeneTools software (unlimited copies)
  Analyse date on your own computer

Product specifications

Download brochure

Economical gel documentation – DNA and protein gel imaging your way

Using a compact, InGenuis3 gel documentation system you’re in control. You can image your choice of dyes and stains by choosing UV, blue or white lighting options. The system’s GeneSys software selects the right lighting and filters for you, making it easy to image fluorescent ethidium bromide or SYBR^® Safe DNA gels and protein gels stained with Coomassie Blue or silver.

For an economical system, the InGenius3 offers a 3m pixel camera and can produce images with 16 bit image depth. A manual zoom lens and manual filter drawer (includes a UV filter) completes the package.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Features

DNA and protein gel imaging your way

• Small footprint
  Plenty of bench space for your experiments
• 3m pixel camera
  Detect nanogram amounts on gels (up to 20cm x 20cm)
• Manual zoom
  Puts you in control of the camera
• White, UV and blue lighting options
  Flexibility to image fluorescent DNA and visibly stained protein gels
• High resolution
  InGenius3 uses a high resolution 3m pixel camera with a 16 bit image output
• Manual system
  Allows the user to select filters using a filter drawer, control lighting and the camera lens
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of gel you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data at your own computer.

Product specifications

Syngene is the most popular gel documentation system in New England.

If raw data, high sensitivity, image resolution, an affordable price, and great service are important factors in making your decision for a gel imaging system, contact us or call (617)286-4632.

A high sensitivity chemiluminescent detection system for your Western blot. User defined protocol, no focusing, a three year warranty and great price. Base model under $10K

Dedicated chemiluminescence imaging system – great Westerns without film!

You love the sensitivity that chemi brings to Western blot imaging but hate the drama of using film to get it. Utilising the GeneGnome XRQ’s optimised short ‘camera to sample’ technology, you’ll get more than double the dynamic range of film, making it easy for you to see picogram or femtogram protein levels without all the fuss.

The GeneGnomeXRQ is dedicated to chemiluminescence imaging and is built for high performance and automation, featuring a high quantum efficiency CCD camera.

The compact instrument sits on any laboratory bench taking up very little space. The GeneGnome XRQ requires an external PC for use.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Features

Dedicated chemi imaging system

• Small footprint
  More space for your research
• High quantum efficiency (QE) camera
  Detects your faintest bands
• Automated chemiluminescent capture
  Perfect exposure without film
• Cooled camera
  No annoying background noise on your blots
• Fixed lens controlled by GeneSys software
  One click and you’ll image any manufacturer’s chemi reagents
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of blot you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data on your own computer
• Optimised – for imaging chemiluminescence Western blots
  GeneGnome XRQ is configured for maximum sensitivity to ensure even the faintest band on a blot can be captured.
• Sensitive cooled camera
  The high quantum efficiency cooled CCD camera is very sensitive to low level light emissions from a blot. The peltier cooled camera has exceptional ‘signal to noise’ performance resulting in virtually undetectable background noise. The short ‘camera to sample’ distance further enhances the ability to work with chemiluminescence samples and reagents. When compared to film, the GeneGnome XRQ has more than double the dynamic range. This allows for extremely accurate quantification.
• Small footprint
  The GeneGnome XRQ has a very small footprint and takes up minimal bench space. The automatic slide-out drawer allows easy sample handling. The fixed aperture and focus of the lens results in a very simple set-up procedure making image capture as simple as a click of a mouse button.

Specifications

Syngene is the most popular gel documentation system in New England

If raw data, high sensitivity, image resolution, an affordable price, and great service are important factors in making your decision for a gel  imaging system, contact us or call (617)286-4632.

Compact fluorescent and chemi Western blot imaging system

Need to quantify multiple different fluorescent proteins on one blot and capture images of chemi blots, but your lab is limited on space? Then the G:BOX mini is just the compact imaging powerhouse you’ve been looking for. With stain-free, RGB and IR excitation options for Alexa Fluor^® 488, 546, 647 and IR dyes, you’re just a click away from brilliant multiplex images from one single Western.

Using the G:BOX mini you’ll also get perfectly exposed images of your chemi labelled proteins without the bother of film. Simply place your blot in the darkroom, click on GeneSys capture software and your imager will do the rest with no fuss and no messy chemicals.

G:BOX mini is a compact, multi-application imaging system combining a unique motor driven stage and cooled high resolution 6 or 9 megapixel camera enabling you to generate accurate optical images, not just digitally enhanced ones. With a G:BOX mini you’ll see separate close chemi and fluorescent bands or spots even on complex gels and know they’re really part of your data.

HI-LED lighting options  cover the full spectrum of high intensity blue, green, red and infra-red resulting in faster exposure times and publication quality images.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Feature

Compact fluorescent and chemi Western blot imaging system

• Small footprint
  Leaves plenty of room on any lab bench
• RGB and IR HI-LED lighting options
  Fast quantification of multiple fluorescent proteins without stripping and re-probing
• Stain-free imaging capability
  Capture images of TGX Stain-Free™ FastCast™ acrylamide gels and many more
• High quantum efficiency (QE) camera
  Detect picogram or femtogram amounts
• Luxury lens (F/0.95 motor driven) with data feedback
  Captures the highest quality images
• Automatic motor driven stage with automated focus
  For real, optical images
• White, UV and blue lighting options
  Image all gels and blot types on one system
• Cleverly designed screen mount option
  Easily and securely attach a monitor
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of gel you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data at your own computer

Specifications

Detection with a difference

Syngene is the most popular gel documentation system in New England.

If raw data, high sensitivity, image resolution, an affordable price, and great service are important factors in making your decision for a gel  imaging system, contact us or call (617)286-4632.

Versatile high resolution gel doc

An entry level system for imaging fluorescence and visible applications, the G:BOX F3 gel doc is the ideal solution for your laboratory.

Using your choice of dyes or stains, the G:BOX F3 automatically selects the right lighting and filters to detect close bands on both small and large gels. Choosing white light options for Coomassie Blue, UV and blue lighting options, ethidium bromide or SYBR^® Safe gels, this system is the ultimate in gel doc flexibility.

The stylish and modular designed G:BOX F3 gel doc system includes a high resolution 5m pixel camera which is capable of giving outstanding images with incredible spatial resolution as well as a motor driven zoom lens and a motor driven filter wheel as standard. G:BOX F3 also comes with a Lens Feedback option allowing you to optimise your image capture using user protocols.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Features

Gel imaging for fluorescence and visible applications

• Spacious darkroom
  Image gels up to 32cm x 24cm
• 5m pixel camera
  Resolves close bands and detects nanogram amounts
• Motor driven zoom lens and filter wheel
  One click set up for easy image capture
• Optional Lens Feedback available
  Optimise image capture by using user protocols
• White UV and blue lighting options
  Flexibility to image fluorescent and visible stained gels
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of gel you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data at your own computer

Specifications

Syngene is the most popular gel documentation system in New England

If raw data, high sensitivity, image resolution, an affordable price, and great service are important factors in making your decision for a gel  imaging system, contact us or call (617)286-4632.

Walk Away Western Blot Imaging

Your lab’s imaging system shouldn’t control how you detect proteins on Western blots. Chemiluminescence is great if you want sensitive detection of picogram or femtogram amounts, while fluorescence lets you quantify and detect multiple different proteins on one blot. With a G:BOX Chemi XX6/XX9 you can have it all. Powered by Syngene’s revolutionary GeneSys software featuring hundreds of imaging protocols, you’re free to choose chemiluminescence and fluorescence reagents from any manufacturer, putting you in charge of how you detect your proteins.

Featuring an extended darkroom, you can choose between a 6 or 9 mega pixel, cooled, high quantum efficiency camera for unrivaled levels of sensitivity with minimal background interference.

HI-LED lighting options  cover the full spectrum of high intensity blue, green, red and infra-red resulting in faster exposure times and publication quality images. An edge lighting option can also be used for 2D gel capture including the use of DIGE gels.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Features

Gel imaging for fluorescence and chemiluminescence

• High quantum efficiency (QE) camera
  For unrivalled levels of sensitivity
• Fast chemiluminescence detection
  Walk-away image capture without film
• Motor driven lens and filter wheel
  Easy to use, fully automated set up
• IR and RGB HI-LED lighting options
  Multiplex fluorescence and protein quantification
• Stain-free imaging capability
  Capture images of TGX Stain-Free™ FastCast™ acrylamide gels and many more
• Edge lighting option
  2D and multiplex in-gel fluorescence DIGE image capture
• White, UV and blue lighting options
  Capture all types of gel and blot images with one system
• Extended darkroom with motor driven stage
  Easily image large gels and blots
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of gel you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data at your own computer

Specifications

Syngene is the most popular gel documentation system in New England.

If raw data, high sensitivity, image resolution, an affordable price, and great service are important factors in making your decision for a gel  imaging system, contact us or call (617)286-4632.

G:BOX CHEMI XX6

For high performance imaging, the G:BOX Chemi series systems provide the user with an extended range of applications covering fluorescence and chemiluminescence.

Walk Away Western Blot Imaging

Your lab’s imaging system shouldn’t control how you detect proteins on Western blots. Chemiluminescence is great if you want sensitive detection of picogram or femtogram amounts, while fluorescence lets you quantify and detect multiple different proteins on one blot. With a G:BOX Chemi XX6/XX9 you can have it all. Powered by Syngene’s revolutionary GeneSys software featuring hundreds of imaging protocols, you’re free to choose chemiluminescence and fluorescence reagents from any manufacturer, putting you in charge of how you detect your proteins.

Featuring an extended darkroom, you can choose between a 6 or 9 mega pixel, cooled, high quantum efficiency camera for unrivaled levels of sensitivity with minimal background interference.

HI-LED lighting options  cover the full spectrum of high intensity blue, green, red and infra-red resulting in faster exposure times and publication quality images. An edge lighting option can also be used for 2D gel capture including the use of DIGE gels.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Features

Gel imaging for fluorescence and chemiluminescence

• High quantum efficiency (QE) camera
  For unrivalled levels of sensitivity
• Fast chemiluminescence detection
  Walk-away image capture without film
• Motor driven lens and filter wheel
  Easy to use, fully automated set up
• IR and RGB HI-LED lighting options
  Multiplex fluorescence and protein quantification
• Stain-free imaging capability
  Capture images of TGX Stain-Free™ FastCast™ acrylamide gels and many more
• Edge lighting option
  2D and multiplex in-gel fluorescence DIGE image capture
• White, UV and blue lighting options
  Capture all types of gel and blot images with one system
• Extended darkroom with motor driven stage
  Easily image large gels and blots
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of gel you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data at your own computer

Specifications

Specifications

Syngene is the most popular gel documentation system in New England.

If raw data, high sensitivity, image resolution, an affordable price, and great service are important factors in making your decision for a gel imaging system, contact us or call (617)286-4632.

Cost-efficient chemi imaging and gel doc

For a laboratory that needs hassle-free chemiluminescent detection, as well as routine gel documentation, using the G:BOX Chemi XRQ’s powerful GeneSys software to switch between applications is simplicity itself. Place your chemi blot in, and the system’s cooled camera captures images with a sensitivity equal to film or slide in your gels to generate quality pictures of your DNA and proteins anytime you want.

Featuring a standard darkroom and a 4 million pixel image resolution, the G:BOX Chemi XRQ camera is cooled to provide a low signal to noise ratio with perfect background.

HI-LED lighting options  cover the full spectrum of high intensity blue, green, red and infra-red resulting in faster exposure times and publication quality images.

The G:BOX Chemi XRQ is a cost-effective alternative to laser based technology offering a faster workflow for imaging complex multiplex fluorescent gels and blots.

The system is controlled by GeneSys application driven image capture software and comes complete with unlimited copies of GeneTools analysis software.

Features

Gel imaging for fluorescence and chemiluminescence

• High quantum efficiency (QE) camera
  Picogram detection
• Multiplex imaging of up to 5 different channels with UV, blue and RGB HI-LED lighting options
  Easily switch between blot or gel imaging
• Stain-free imaging capability
  Capture images of TGX Stain-Free™ FastCast™ acrylamide gels and many more
• Auto-exposure
  Perfectly exposed chemi images without film
• Excellent signal to noise ratio
  No annoying backgrounds on your blots
• Protocol driven image capture
  No camera expertise needed for great results
• Motor driven lens and filter wheel
  Simple, automated set up
• Reproducible and quantifiable data
  Accurate results time after time
• CFR21 Part 11 compliant
  Fully traceable results suitable for regulatory audits
• GeneSys application driven image capture software
  Contains extensive database of dyes and imaging protocols. All you need to know is the type of gel you’re using and GeneSys automatically selects the optimal lighting and filters to produce the perfect image
• GeneTools analysis software (unlimited copies)
  Analyse data at your own computer

Specifications

Galileo Reflection™ 1010 Dual-Gel Vertical Electrophoresis Unit

by Galileo bioscience

Run either one or two gels simultaneously on these versatile separation systems. The 10x10cm size of the system also accomodates most pre-cast gels.

Complete double sided vertical system for running one or two gels, in a 10 x 10 cm format. Unique casting bases allows both casting and running of gels without unclamping from the upper buffer chamber, providing for safer and more convenient gel handling. In addition the 1010 device will accommodate most precast gel cassettes on the market.

Water cooling feature is included for protocols that require it. Connections are easily made by attaching standard tubing over the 3/8″ barbed in/out ports provided on the device. Water may be provided by tap or other temperature controlled water source. Optional alumina backer plates may be used to facilitate cooling efficiency and uniformity, and are available in the accessories list below.

System Features

The GalileoReflection™ 85-1010 complete system includes these features:

• Heavy duty upper buffer chamber with cooling port connections.
• Lower buffer chamber.
• Interlock safety lid with attached leads.
• Casting base.
• Two-pack each of plain & notched glass plates.
• One acrylic blocker plate (used when running only one gel).
• Ttwo 10-well, 0.8mm thick combs
• Four 0.8mm thick side spacers.

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Alumina cooling plate. For use with cooling systems. This plate can be sandwiched between the gel and the inner buffer chamber to improve overall temperature uniformity.
• Casting base. For quick, efficient and leak-proof casting.
• Multiple gradient caster.

View the Galileo Bioscience electrophoresis and blotting system catalog

The RapidCast  gel casters is an “U” shaped acrylic caster which is sized to seal against the ends of the 12cm x 14cm gasketed trays. RapidCast casters hold up to three corresponding trays and are availble with or without trays.

A set of replacement gaskets for the RapiCast gel tray.  Can be used for new or existing horizontal gel electrophoresis 7cm x 8 cm gel trays.

A set of replacement gaskets for the RapiCast gel tray.  Can be used for new or existing horizontal gel electrophoresis 9cm x 11cm gel trays.

The RapiCast 7cm x 8cm gel caster pack includes 9cm x 11cm gel casting system and three 9cm x 11cm gel trays. A complete system for rapidly casting gels!

The RapiCast gel caster can be used for casting up to three 9cm x 11cm gels at once. Gel trays are not included.

The RapiCast gel tray can be used for new or existing horizontal gel electrophoresis systems which accommodate 9cm x 11cm gels.

RapiCast 9 teeth gel comb, 1.5 mm thickness, for 0911 system.

Galileo Reflection™ 2020 Dual-Gel  Vertical Electrophoresis Unit

by Galileo bioscience

Run either one or two extra wide long-run gels simultaneously on these versatile separation systems. 

The 2020 unit is designed to provide the researcher with both high cample capacity and increased run length. Runs either one or two larger format 20cm wide x 20cm tall gels. Unique casting base allows both casting and running of the gel without unclamping from the upper buffer chamber, providing for safer and more convenient gel handling.

Water cooling feature is included for protocols that require it. Connections are easily made by attaching standard tubing over the 3/8″ barbed in/out ports provided on the device. Water may be provided by tap or other temperature controlled water source. Optional alumina backer plates may be used to facilitate cooling efficiency and uniformity, and is shown in the accessories list below.

System Features

The Galileo Reflection™ 85-2020 complete system includes these features:

• Heavy duty upper buffer chamber with cooling port connections.
• Lower buffer chamber.
• Interlock safety lid with attached leads.
• Casting base.
• Four-pack each of plain & notched glass plates
• One acrylic blocker plate (used when running only one gel)
• Two 15-well, 1.5mm thick combs.
• Two 20-well, 1.5mm thick combs.
• Eight 1.5mm thick side spacers

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Alumina cooling plate. For use with cooling systems. This plate can be sandwiched between the gel and the inner buffer chamber to improve overall temperature uniformity.
• Casting base. For quick, efficient and leak-proof casting.

View the Galileo Bioscience electrophoresis and blotting system catalog

Galileo Reflection™ 1614 Dual-Gel large-Format Vertical Electrophoresis Unit

by Galileo bioscience

Run either one or two large format gels simultaneously on these versatile separation systems. 

The 1614 unit is the ideal unit for separation of complex analytes. Designed to run one or two larger format 16cm wide x 14cm tall gels, the unit provides longer run lengths and increased separation capacity. The unique casting base allows both casting and running of the gel without unclamping from the upper buffer chamber, providing for safer and more convenient gel handling.

Water cooling feature is included for protocols that require it. Connections are easily made by attaching standard tubing over the 3/8″ barbed in/out ports provided on the device. Water may be provided by tap or other temperature controlled water source. Optional alumina backer plates may be used to facilitate cooling efficiency and uniformity, and is shown in the accessories list below.

System Features

The GalileoReflection™ 85-1614 complete system includes these features:

• Heavy duty upper buffer chamber with cooling port connections.
• Lower buffer chamber.
• Interlock safety lid with attached leads.
• Casting base.
• Four-pack each of plain & notched glass plates
• One acrylic blocker plate (used when running only one gel)
• Two 10-well, 1.5mm thick combs.
• Two 15-well, 1.5mm thick combs.
• Eight 1.5mm thick side spacers

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Alumina cooling plate. For use with cooling systems. This plate can be sandwiched between the gel and the inner buffer chamber to improve overall temperature uniformity.
• Casting base. For quick, efficient and leak-proof casting.

View the Galileo Bioscience electrophoresis and blotting system catalog

Galileo Reflection™ 2010 Dual-Gel Vertical Electrophoresis Unit

by Galileo bioscience

Run either one or two gels simultaneously on these versatile separation systems. 

Similar to the 1010 unit but designed to run one or two larger format 20cm wide x 10cm tall gels. Unique casting base allows both casting and running of the gel without unclamping from the upper buffer chamber, providing for safer and more convenient gel handling.

Water cooling feature is included for protocols that require it. Connections are easily made by attaching standard tubing over the 3/8″ barbed in/out ports provided on the device. Water may be provided by tap or other temperature controlled water source. Optional alumina backer plates may be used to facilitate cooling efficiency and uniformity, and is shown in the accessories list below.

System Features

The GalileoReflection™ 85-2010-V complete system includes these features:

• Heavy duty upper buffer chamber with cooling port connections.
• Lower buffer chamber.
• Interlock safety lid with attached leads.
• Casting base.
• Two-pack each of plain & notched glass plates
• One acrylic blocker plate (used when running only one gel)
• Two 15-well, 0.8mm thick combs.
• Two 20-well, 0.8mm thick combs.
• Eight 0.8mm thick side spacers

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Alumina cooling plate. For use with cooling systems. This plate can be sandwiched between the gel and the inner buffer chamber to improve overall temperature uniformity.
• Casting base. For quick, efficient and leak-proof casting.

View the Galileo Bioscience electrophoresis and blotting system catalog

RapiCast 9 teeth gel comb, 1 mm thickness, for 0911 system.

RapiCast 8 teeth gel comb, 1mm thickness, for 0911 system.

RapiCast 8 teeth gel comb, 1.5 mm thickness, for 0911 system.

RapiCast 8 teeth gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 8 teeth gel comb, 1 mm thickness, for 0708 system.

The RapiCast gel tray can be used for new or existing horizontal gel electrophoresis systems which accommodate 7cm x 8 cm gels.

The RapiCast 7cm x 8cm gel caster pack includes 7cm x 8 cm gel casting system and three 7cm x 8 cm gel trays. A complete system for rapidly casting gels!

The RapiCast gel caster can be used for casting up to three 7cm x 8 cm gels at once. Gel trays are not included.

RapiCast 6 teeth gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 6 teeth gel comb, 1 mm thickness, for 0708 system.

RapiCast 5 teeth gel comb, 1mm thickness, for 0911 system.

RapiCast 5 teeth gel comb, 1.5 mm thickness, for 0911 system.

RapiCast 5 teeth gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 5 teeth gel comb, 1 mm thickness, for 0708 system.

RapiCast 2 teeth preparative gel comb, 1 mm thickness, for 0911 system.

RapiCast 2 teeth preparative gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 18 teeth gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 18 teeth gel comb, 1 mm thickness, for 0911 system.

1515 Gel Unit

by Galileo bioscience

Extra width for increased sample thru-put. Holds up to 112 samples.Unit features RapidCast trays for quick in-unit gel casting of 12cm wide by 14cm long gels.

System description

The 1515 is ideal for guick screening of multiple samples, and if you choose Galileo microtiter combs, quick multi-channel loading too! The unit features the Galileo ExpressCast gel casting system for quick, tape-free gel casting and includes a built-in bubble level and leveling screws for convenient level adjustment. You may choose from a wide variety of comb options to customize your order.

System Features

The Galileo 1515 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• End gated 15cm wide x 15cm long ExpressCast™ UV-transparent gel tray with built-in fluorescent ruler and 14 comb slots.
• Two 1.5mm x 17 tooth combs
• Two 1.5mm x 34 tooth combs

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Additional gel trays.
• A wide range of comb options.
• Gel loading guides. These guides fit into the comb slots of the gel tray, and have precision machined slots that provide accurate aligning of your multi-channel pipet during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

RapiCast 14 teeth gel comb, 1 mm thickness, for 0911 system.

RapiCast 14 teeth gel comb, 1 mm thickness, for 0911 system.

1214 Mini Gel Unit

by Galileo bioscience

This flexible system from Galileo is the perfect personal unit for a wide range of separation needs, and our most popular model.

Unit features RapidCast trays for quick in-unit gel casting of 12cm wide by 14cm long gels.

System description

Choose a complete system or build your own custom unit from the many system components we offer.  The G-80-1214 gel system is supplied with a RapidCast™ gasketed gel tray for convenient gel casting directly in the buffer chamber.  Choose from a wide variety of comb options.  All are compatible with Owl Separation Systems B2A or similar devices.  The teeth on combs marked as “microtiter” are uniformly spaced for easy loading with multichannel pipettors.System features

System Features

The 80-1214 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• Gasketed (cast in place) 12cm wide x 14cm long UV-transparent gel tray with
• built-in fluorescent ruler and 2 comb slots.
• One 1.5mm x 12 tooth comb
• One 1.5mm x 20 tooth comb

System Options

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• RapidCast casting base G-80-1214-RCGC. Accommodates up to three 1214 RapidCast gel trays for casting outside buffer chamber.
• Gel loading guide G-80-1214-MT2SLG. This guide fits into the comb slots of the gel tray, where it’s precision machined slots provide accurate positioning for your multi-channel pipet during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

RapiCast 12 teeth gel comb, 1.5 mm thickness, for 0911 system.

RapiCast 12 teeth gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 12 teeth gel comb, 1 mm thickness, for 0911 system.

RapiCast 12 teeth gel comb, 1 mm thickness, for 0708 system.

RapiCast 10 teeth gel comb, 1mm thickness, for 0911 system.

RapiCast 10 teeth gel comb, 1.5 mm thickness, for 0911 system.

RapiCast 10 teeth gel comb, 1.5 mm thickness, for 0708 system.

RapiCast 10 teeth gel comb, 1 mm thickness, for 0708 system.

0911 Mini Gel Unit

by Galileo bioscience

The Galileo 0911 is a mini-gel unit with extended run length for improved resolution. It also features a RapidCast gasketed tray for quick in-unit gel casting.

System description

The standard 0708 mini gel system includes a RapiCast™ gasketed gel tray for convenient gel casting right in the buffer chamber.

System features

The 0911 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• Gasketed (cast in place) 9cm wide x 11cm long UV-transparent gel tray with built-in fluorescent ruler and 2 comb slots.
• One 1.5mm x 10 tooth comb
• One 1.5mm x 14 tooth comb

View available accessories: RapiCast 0911 Accessories

View the Galileo Bioscience electrophoresis and blotting system catalog

0708 Mini Gel Unit

by Galileo bioscience

Perfectly sized for rapid analysis of small analytes like PCR and RE fragments. This unit features a RapidCast gasketed tray for quick in-unit gel casting.

System description

The standard 0708 mini gel system includes a RapiCast™ gasketed gel tray for convenient gel casting right in the buffer chamber.

System features

The 0708 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• Gasketed (cast in place) 7cm wide x 8cm long UV-transparent gel tray with built-in fluorescent ruler and 2 comb slots.
• One 1.5mm x 6 tooth comb
• One 1.5mm x 10 tooth comb

View available accessories: RapiCast 0708 Accessories

View the Galileo Bioscience electrophoresis and blotting system catalog

Download brochure                                 contact us

An automated cell counter has never been this easy or affordable.

• Fully automated cell counting and cell viability analysis.
• Autofocus technology for fast and reliable cell counting.
• Trypan blue stained cell counting or non-stained cell counting methods.
• Various histograms and cell-size gating.
• Unmatched counting accuracy and speed.
• Built-in computer and printer.
• The most affordable running cost currently on the market. Don’t spend more money and waste time on slides that require you to peel off a protective film! 

The Luna-II automated cell counter is the most advanced cell counter with unmatched speed, accuracy, and consistency of measurement. It is a stand-alone instrument integrating precision microscopy optics, an onboard PC, image analysis software, automatic focusing, and an optional built-in printer.

The Luna-II accurately detects total/live/dead cells at concentrations ranging from 5×10-4 cells/ml to 1×10-7 cells/ml and cell sizes between 3um and 60um.

NEW AUTOFOCUSING TECHNOLOGY

The LUNA-II™ automated cell counter has integrated a novel focusing mechanism based on liquid lens technology.
The liquid lens does not use any mechanical moving parts to change the Z stage. Instead, the Z position of the sample is rapidly
obtained by the application of a small voltage to the liquid lens. The elimination of moving parts removes noise and significantly
reduces the need for servicing. Even after multi-million cycles of focusing, the liquid lens does not require repair or service.
In combination with this novel focusing mechanism, the LUNA-II™ has integrated a new autofocusing algorithm optimized for
cell counting.

Cell Counting Accuracy: Declustering

The LUNA-II™ automated cell counting algorithm has been recognized to have the best-in-class cell counting accuracy. The LUNA™ software has exceptional accuracy in cell de-clustering and can successfully count clumpy cells. The LUNA-II™ automated cell counter has inherited this well-known performance aspect of the LUNA™ software. Clumpy cells are de-clustered quickly and automatically, then counted as individual cells.

Reduced Running Cost

Automated cell counters utilize disposable counting slides to eliminate washing steps of manual cell counting with the glass hemocytometer. Although disposable cell counting slides have several advantages, the increased running cost has been a substantial concern. Logos Biosystems developed a patented T-BOND technology to manufacture precision cell counting slides more efficiently. Therefore, the unit price of counting slides became much more affordable, providing significant cost savings.

Built-in Thermal Printer (optional)

A thermal printer is integrated in the LUNA-II™ automated cell counter, and the counting results can be printed immediately for record keeping purposes. Because the printer is already integrated in the LUNA-II™ automated cell counter, an additional cable connection is not required.

Interactive Software Interface

Options for  staining methods

The LUNA-II™ automated cell counter can count samples with or without trypan blue dye. The selection of trypan blue presence
or absence can easily be chosen in the settings menu.

Cell size histogram and cell size based gating

After counting, cells can be gated based on their size information provided by the LUNA-II™. The specific size of cell populations
Can easily be included or excluded on histograms.

Cell cluster map

Counted cells can be sorted with cell cluster map, into single cells, doublets, or triplets. The cell cluster map can be used to monitor changes in culture conditions or cell isolation/preparation protocols.

Review and Re-analysis option

The LUNA-II™ automated cell counter provides a powerful review option. A separate PC unnecessary. Users can open cell images directly on the LUNA-II™ automated cell counter to check previous results.

Various file save options

The LUNA-II™ can store up to 1,000 counts onboard. After counting, the result is automatically saved in the memory, and previous count results can be exported via USB as a .CSV file for further analysis. The results and image data can be saved in three different file formats such as TIF, annotated TIF, or a PDF report file. The PDF report file contains all the data generated during/after the cell counting, i.e., the protocol used, cell counting results, date, raw/analyzed cell image(s), and histograms are included in the PDF report file.

Download brochure                                 contact us

An fluorescent automated cell counter has never been this easy or affordable.

• Dual fluorescence optics for sensitive cell analysis
• Trypan blue stained cell counting with bright field optics
• Unmatched cell counting accuracy
• Optimized for primary cells, stem cells, PBMCs, splenocytes, etc.
• Most affordable counting cost
• Cell size gatingInteractive graphic user interface

Dual Fluorescence Cell Counting

The LUNA-FL™ Dual Fluorescence Cell Counter from Logos Biosystems is a quantum leap forward for automated cell counting and cell viability analysis. The LUNA-FL™ Dual Fluorescence Cell Counter gives you sensitive and accurate live/dead counts without  cell type restrictions. Unlike immortalized cell lines, primary cells such as PBMCs, splenocytes, neutrophils, and stem cells have been difficult to count with conventional cell counters such as the Coulter counter or automated image-based cell counters utilizing  bright field optics. Primary cells are often contaminated with undesirable debris that can be miscounted as cells with conventional  cell counters. The LUNA-FL™ is equipped with dual fluorescence optics to overcome this problem. Live and dead cells are stained  with green and red fluorescence dye, respectively, and subsequent cell images are analyzed with accurate image analyzing software

To read a general review of fluorescent cell counting, please click here.

Bright Field Optics For Trypan Blue Cell Counting

The LUNA-FL™ has inherited the proven performance of the LUNA™. The precision bright field optics of the LUNA™ has been integrated into the LUNA-FL™ to provide the convenience of trypan blue cell counting. The powerful and precise cell counting  algorithm of the LUNA™ is used in the LUNA-FL™ LUNA-FL™ = LUNA™ + Dual fluorescence cell counter

Cell Counting Accuracy: Declustering

The LUNA-II™ automated cell counting algorithm has been recognized to have the best-in-class cell counting accuracy. The LUNA™ software has exceptional accuracy in cell de-clustering and can successfully count clumpy cells. The LUNA-II™ automated cell counter has inherited this well-known performance aspect of the LUNA™ software. Clumpy cells are de-clustered quickly and automatically, then counted as individual cells.

GFP Transfection Efficiency Assay

With the LUNA-FL™ Dual Fluorescence Cell Counter, GFP expression analysis takes less than 30 seconds. Bright field and fluorescence cell images are analyzed to detect GFP-positive and negative cells, and a corresponding fluorescence intensity histogram is displayed for further analysis. The LUNA-FL™ Dual Fluorescence Cell Counter is integrated with on-board flow cytometry type gating software. Be confident in the accuracy of your results by adjusting the threshold of fluorescence intensity.

Reduced Running Cost

Automated cell counters utilize disposable counting slides to eliminate washing steps of manual cell counting with the glass hemocytometer. Although disposable cell counting slides have several advantages, the increased running cost has been a substantial concern. Logos Biosystems developed a patented T-BOND technology to manufacture precision cell counting slides more efficiently. Therefore, the unit price of counting slides became much more affordable, providing significant cost savings.

Compact and Fast Thermal Printer (optional)

LUNA-FL™ provides a compact mobile printer for further record keeping purpose. Thermal roll paper or label paper can be selected. This plug & play mobile printer is ready-to-use after the USB to USB connection.

Interactive Software Interface

Options for  staining methods

The LUNA-II™ automated cell counter can count samples with or without trypan blue dye. The selection of trypan blue presence
or absence can easily be chosen in the settings menu.

Cell size histogram and cell size based gating

After counting, cells can be gated based on their size information provided by the LUNA-II™. The specific size of cell populations
Can easily be included or excluded on histograms.

Cell cluster map

Counted cells can be sorted with cell cluster map, into single cells, doublets, or triplets. The cell cluster map can be used to monitor changes in culture conditions or cell isolation/preparation protocols.

Review and Re-analysis option

The LUNA-II™ automated cell counter provides a powerful review option. A separate PC unnecessary. Users can open cell images directly on the LUNA-II™ automated cell counter to check previous results.

Various file save options

The LUNA-II™ can store up to 1,000 counts onboard. After counting, the result is automatically saved in the memory, and previous count results can be exported via USB as a .CSV file for further analysis. The results and image data can be saved in three different file formats such as TIF, annotated TIF, or a PDF report file. The PDF report file contains all the data generated during/after the cell counting, i.e., the protocol used, cell counting results, date, raw/analyzed cell image(s), and histograms are included in the PDF report file.

ULTRASENSITIVE. RELIABLE. COMFORTABLE.

The Lumat LB 9510 offers the functionality, versatility and superior performance you can expect from a luminometer developed by Berthold Technologies. The optimized optical system provides true single photon counting combined with a low-noise photomultiplier tube for up to 6 decades of linear dynamic range. The new Lumat has all the key features needed for today’s research applications.

Ready to meet your application needs

The new Lumat is a tube luminometer that uses state-of-the-art technology based on more than 40 years of experience engineering and designing luminometers. The luminometer supports all basic luminescence technologies including:

• Flash-type Luminescence
• Glow-type Luminescence
• Bio-Luminescence
• Chemi-Luminescence

Luminescence detection at its best

Thanks to a stringent selection of photomultipliers working in photon counting mode and more than 40 years of experience building luminometers, the new Lumat offers excellent luminescence sensitivity: <1 zmol firefly luciferase and <1 amol ATP/tube (high sensitivity model) can be reliably detected.

JET injectors – highest accuracy, speed and cell-friendliness

The Lumat can be equipped with up to 2 JET injectors with variable volumes. The ultra-fast injection speed of JET-injectors eliminates any delay between injection and measurement and is critical to measure fast reactions, e.g. for flash luminescence measurements.

Berthold Technologies’ JET injectors use Teflon bellows for accurate and fast injections and guarantee most efficient mixing as well as extreme longevity.

• Accurate pipetting of small volumina: regardless of whether you want to inject large or small volumes, JET injectors ensure high accuracy and more than 98% accuracy over the entire volume range
• Low maintenance costs: frictionless operation for extended lifetime
• Cell-friendly performance: cell-friendly materials and negligible shear forces enable worry-free injection of cell suspensions, e.g. in Aequorin-based calcium assays

Convenient sample switching mechanism

The measurement of individual samples one after the other can be time-consuming. The Lumat has a turret mechanism that makes this job easier and increases your throughput. Thanks to its motor-driven revolving magazine mechanism based on a rotating chamber for two tubes (one for measuring and one for loading and unloading), so you can prepare and insert the next sample while the previous one is still measuring.

Powerful software

LightCompass® is a flexible software enabling easy data acquisition, analysis and reporting using Berthold Technologies’ instruments. It has been optimized for different microplate and tube formats. LightCompass® features all the functions you can expect from an advanced scientific software, such as flexible creation of measurement protocols, curve fitting, qualitative analysis and compliance with FDA 21 CFR Part 11.

Galileo Insight™ Semi-Dry Blotting Systems

by Galileo bioscience

Choose Galileo Insight™ semi-dry sytems for rapid and efficient molecular transfer

Galileo semi-dry electroblotters provide quick and efficient transfer of nucleic acids and proteins from agarose or acrylamide gels. Since only the tranfer “sandwich” of gel, membrane and blotting papers must be kept wet, much less buffer is required than traditional tank transfer systems. Solid plate style electrodes (stainless steel cathode and platinum anode) assure even and complete molecular transfer.

G91-1010-SD System

Low cost and quick transfer times make this system is ideal for the rapid blotting of small pre-cast and self-cast gels. The 1010-SDBLT device will easily accomodate almost all pre-cast gels, and for many larger format pre-cast gels, once the stacking area of the gel is removed the “working” area of will also fit easily into the 1010-SDBLT device. System is supplied complete with power leads and a sample pack of our ultra-pure cotton fiber filter paper.

G91-2020-SD System

The larger format 2020 system is ideal for transfer of larger gels or simultaneous transfer of multiple smaller gels. System is supplied complete with power leads and a sample pack of our ultra-pure cotton fiber filter paper.

View the Galileo Bioscience electrophoresis and blotting system catalog

Insight Mini Tank Blotter

by Galileo bioscience

A tank style blotting sytems for reliable and efficient molecular transfer of even “hard to transfer” compounds.

This tank style electroblotter provides reliable and efficient transfer of a wide range of protein coumpounds from acrylamide gels. Up to four gels can be transfered simultaneously. Platinum grid style electrodes and robust construction assure even and complete molecular transfer and long service life. System is supplied complete with power leads and four blotting cassetes. Also included is a sample pack of our ultra-pure cotton fiber filter paper.

View the Galileo Bioscience electrophoresis and blotting system catalog

HERM LB500 with Nal detector for gamma and high energy beta isotopes

The HERM is a dedicated radio HPLC monitor which can be connected to different detectors providing flexibility, reproducibility and sensitivity. The HERM offers a safe and user-friendly solution for all quality control laboratories. The HERM with NaI detector for gamma and high energy beta isotopes combines an extremely sensitive NaI detector with compact shielding and can detect even low energy gamma isotopes like 125I with high efficiency. For PET and direct luminescence, the HERM with fLumo detector is available.

Simple integration into every HPLC system

The HERM makes integration into any existing HPLC system very easy. The PC connection can be established instantly via the USB port or by using the analog 0-1 V output. Its compact design makes it easy to fit in to a hot cell.

Sensitive and reliable measurement

The NaI detector option combines an extremely sensitive detector with a compact shielding. Even low energy gamma isotopes like 125I can be detected with high efficiency. Lead shielding ensures low backgrounds even when there is high external radiation.

Easy operation and high flexibility

The HERM LB 500 has been designed to be intuitive and easy to use. This will get you up and running as quickly as possible. Standard tubing is used to create the flow cell volume and provides maximum flexibility. Changing cells is very easy because of the twin cell changer that enables the user to easily switch between two different cell volumes. If required by GLP regulations, the cell volume can be fixed to just one volume using the optional single volume insert. The system has been designed to avoid accidental parameter modifications eliminating manual adjustment as all instrument parameters are controlled remotely.

Dual operation mode

The HERM system can be installed in multiple distinct configurations, providing more flexibility and convenience. The comfortable stand-alone configuration provides an analog signal which can be easily integrated into an existing HPLC system. The system is equipped with a flash memory and a powerful CPU. Alternatively, the system can be installed in the PC-controlled configuration via a USB connection for digital data acquisition.

Easy-to-use software for maximum productivity

The HERM Controller is the software interface to the instrument; it controls all functions and collects the data. The RadioStar software combines the ability to run sophisticated measurements with a user-friendly interface. A Chromeleon™ driver is available, Chromeleon™ is known as a very versatile chromatography software package supporting many different hardware solutions. The driver is fully certified and digitally signed by Thermo Scientific™ and runs with versions 6.x and 7.x.

Specifications:

Detection unit: State-of-the-art ultrasensitive PMT coupled 1 inch NaI detector
Interface: USB port (mini USB connector)
Outputs: TTL signal output (raw data), analog signal 0-1 V with 16-bit resolution, 2 programmable relay outputs
Software: The following options are available: 1. External control and evaluation via RadioStar software or 2. External control and evaluation via Chromeleon™ driver.
Power Supply: 6 V DC (via wide range mains adapter)
Dimensions (W x D x H): Electronics: 210 x 60 x 120 mm, NaI detector: 140 x 180 x 100 mm, Lead shielding: 150 x 350 x 180 mm
Weight: Electronics: 1 kg, NaI detector: 2 kg, Lead shielding: 25 kg.

HERM LB500 with fLumo detector for gamma and high energy beta isotopes

The HERM is a dedicated radio HPLC monitor which can be connected to different detectors providing flexibility, reproducibility and sensitivity. The HERM with fLumo Chemiluminescence detector for HPLC systems uses a highly sensitive head-on photon counting detector with low background which is perfect for PET quality control, among other applications. Different measuring cells can be used to adapt for flow rates, activities and isotopes. For PET and direct luminescence, the HERM with Nal detector is available.

Simple integration into every HPLC system

The HERM makes integration into any existing HPLC system very easy. The PC connection can be established instantly via the USB port or by using the analog 0-1 V output. Its compact design makes it easy to fit in to a hot cell.

Highly sensitive luminescence monitoring

In the fLumo detector the low noise head-on PMT has been designed to face the sample coil directly. The result is a high sensitivity detector for even the faintest traces of chemiluminescence signals.

Background-free Gamma and PET monitoring

The use of specific measuring cells simplifies the measurement of high activity PET isotopes even in high background laboratories.

A bulky and heavy lead shielding is not required as the system is insensitive to 511 keV gamma. Available cells include:

• PET measuring cells
• Luminescence measuring cells
• Gamma measuring cells

Dual operation mode

The HERM system can be installed in multiple distinct configurations, providing more flexibility and convenience. The comfortable stand-alone configuration provides an analog signal which can be easily integrated into an existing HPLC system. The system is equipped with a flash memory and a powerful CPU. Alternatively, the system can be installed in the PC-controlled configuration via a USB connection for digital data acquisition.

Easy-to-use software for maximum productivity

The HERM Controller is the software interface to the instrument; it controls all functions and collects the data. The RadioStar software combines the ability to run sophisticated measurements with a user-friendly interface. A Chromeleon™ driver is available, Chromeleon™ is known as a very versatile chromatography software package supporting many different hardware solutions. The driver is fully certified and digitally signed by Thermo Scientific™ and runs with versions 6.x and 7.x.

Specifications:

Detection unit: Low noise photon counting 1 inch PMT
Interface: USB port (mini USB connector)
Inputs: Start signal (contact closure)
Outputs: TTL signal output (raw data), analog signal 0-1 V with 16-bit resolution, 2 programmable relay outputs
Software: The following options are available: 1. External control and evaluation via RadioStar software or 2. External control and evaluation via Chromeleon™ driver.
Power Supply: 6 V DC (via wide range mains adapter)
Dimensions (W x D x H): Electronics: 210 x 60 x 120 mm, fLumo detector: 225 x 150 x 130 mm
Weight: Electronics: 1 kg, fLumo detector: 4 kg

Maximum Flexibility, Outstanding Sensitivity

In the FlowStar² LB 514 ultimate sensitivity has been combined with touch-screen technology for quick and easy operation. Designed for maximum ease of use, safety and flexibility, the FlowStar² LB 514 sets the new standard for what a radio-HPLC flow detector should be. With over 50 years of experience Berthold Technologies is taking radio-HPLC flow detection to the next level. A wide range of available cells ensures optimal performance and supports full compatibility with both, routine and challenging applications. The convenient dual mode capability enables simple installation in different configurations and makes integration into existing systems easy.

User friendly

The FlowStar² LB 514 is designed to be intuitive and easy to use, to get you up and running quickly. The intuitive touch screen interface makes it easy to get started and keep going. Results are displayed in both, a graphical chromatogram and a numerical format, so you can start interpreting your results in real time while the run is still in progress.

The FlowStar² frees you from configuring parameters manually, thanks to the use of SmartCells: all measuring cells are equipped with a chip to automatically set the correct cell-specific system parameters. In addition, the software includes an extensive isotope library with predefined energy windows and cell usage options (14C, 3H, 32P, 33P, 35S, 128I, 111In, 99mTc…).

Easy integration into your HPLC system

The FlowStar² LB 514 makes integration easy so that everything works together to ensure consistent and reliable results. The integrated A/D converter records signals from external instruments (e.g. UV-detector) without requiring expensive additional hardware, while the USB port enables external control using RadioStar or other HPLC control software (e.g. Chromeleon™).

In addition, the dual analog output allows for the convenient integration into existing HPLC data systems.

The FlowStar² supports UHPLC and other LC technologies:

• UHPLC
• HPLC-MS (Mass Spectrometry)
• HPLC-NMR (Nuclear Magnetic Resonance)

The FlowStar² LB 514 embodies our commitment to providing everything you need for safe and easy integration into your lab environment.

Safety features:

• Automatic HV shutdown for system safety.
• Built-in leak detection to prevent the measuring system from damage caused by aggressive liquids. The system will shut down automatically in the event of cell leakage.

Security features:

• On-board system performance tests with instrument-based history function.
• Password-based multi user access control to protect instrument from unauthorised use.

Validation:

Several test cells are available to perform periodic system performance tests. These cells have been developed to meet GLP/GMP requirements and to guarantee a continuous system performance. Contact us for more information.

High sensitivity

The FlowStar² is the ultimate platform for high-sensitivity radio-HPLC flow detection. It uses random coincidence counting and luminescence subtraction for ultimate performance. In addition, the integrated spectrum scanning feature provides improved optimization of detector setup for each isotope.

The RadioStar software combines the ability to run sophisticated measurements with a user-friendly operation and user interface. In addition, a Chromeleon™ driver is available. Chromeleon™ is known as a very versatile chromatograpy software package supporting many different hardware solutions. The driver is fully certified, digitally signed by Thermo Scientific™ and runs with versions 6.x and 7.x

Choose from a wide range of available SmartCells to meet your application needs. These high sensitivity cells are equipped with a SmartChip to automatically set the correct cell-specific system parameters. The automatic shut-down feature of the system after removal of a cell from the detector provides additional safety.

The range of SmartCells include:

• Liquid scintillation (admixture) cells
• Solid scintillator cells
• Gamma isotopes and Positron Emitter (PET) cells
• Cells for preparative SFC
• Microbore cells for UHPLC and UPLC™
• Special Iodine Cells (125I)
• Cherenkov cells for high energy beta emitters

Specifications

2340 Gel Unit

by Galileo bioscience

For long run lengths, maximum resolution, and really large sample capacity, look no further than the Galileo 2340 device. This unit also features the Galileo ExpressCast system for quick tape-less gel pouring.System description

The 2340 is our maximum capacity system. With a maximum run length of 25cm, the unit can provide very high resolution of complex analytes. Or, fitted with maximum capacity combs in all of the tray’s 12 comb slots, the unit can handle up to 600 samples. The 2340 features the Galileo ExpressCast gel casting system for quick, tape-free gel casting and includes a built-in bubble level and leveling screws for convenient level adjustment. You may choose from a wide variety of comb options to customize your order.

System Features

The Galileo 2340 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• End gated 23cm wide x 40cm long ExpressCast™ UV-transparent gel tray with built-in fluorescent ruler and 12 comb slots.
• Two 1.5mm x 25 tooth combs
• Two 1.5mm x 50 tooth combs

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Additional gel trays.
• A wide range of comb options.
• Gel loading guides. These guides fit into the comb slots of the gel tray, and have precision machined slots that provide accurate aligning of your multi-channel pipet during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

2325 Gel Unit

by Galileo bioscience

Need long run lengths for maximum resolution, and large sample capacity too? Look at the features of the Galileo 2325 unit and we think you will find just what you need.

The 2325 is a full sized large capacity system. With a maximum run length of 25cm, the unit can provide high resolution of complex analytes. Or, fitted for maximum capacity, the unit can handle up to 500 samples. The 2325 features the Galileo ExpressCast gel casting system for quick, tape-free gel casting and includes a built-in bubble level and leveling screws for convenient level adjustment. You may choose from a wide variety of comb options to customize your order.

System Features

The Galileo 2325 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• End gated 23cm wide x 25cm long ExpressCast™ UV-transparent gel tray with built-in fluorescent ruler and 14 comb slots.
• Two 1.5mm x 25 tooth combs
• Two 1.5mm x 50 tooth combs

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Additional gel trays.
• A wide range of comb options.
• Gel loading guides. These guides fit into the comb slots of the gel tray, and have precision machined slots that provide accurate aligning of your multi-channel pipet during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

2314 Gel Unit

by Galileo bioscience

A high-capacity system in a mini-gel size, the Galileo 2314 unit enables rapid separation of large numbers of samples.

The 2314 wide format system accomodates up to 200 samples per run, for quick separation and high thru-put. Because of the wide format of the Galileo 2314 unit, the 23cm wide by 14cm long tray is non-gasketed. Gel casting can be accomplished by taping, or we recommend the G-80-WADJ-CST multi-casting unit for even quicker and more convenient gel casting. The gel tray is UV transmissible, includes an imprinted fluorescent ruler, and has 4 comb slots. Choose from a wide variety of comb options, all with micro-titer spacing for easy loading with multi-channel pipets.

System Features

The Galileo 2314 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• Non-gasketed 23cm wide x 14cm long UV-transparent gel tray with built-in fluorescent ruler and 4 comb slots.
• Four 1.5mm x 50 tooth combs
• Opaque well visualization plate.

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• G-80-WADJ-CST multi casting platform.
• Additional 4 slot gel trays.
• A wide range of comb options.
• Gel loading guides. These guides fit into the comb slots of the gel tray, and have precision machined slots that provide accurate aligning of your multi-channel pipettor during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

1525 Gel Unit

by Galileo bioscience

Perfectly sized for multi-channel sample loading. Holds up to XXX samples.System description

The 1525 is a long run length mini-gel system. With a maximum run length of 25cm, the unit can provide high resolution of complex analytes. Or, fitted for maximum capacity, the unit can handle up to xxx samples. The 1525 features the Galileo ExpressCast gel casting system for quick, tape-free gel casting and includes a built-in bubble level and leveling screws for convenient level adjustment. You may choose from a wide variety of comb options to customize your order.

System Features

The Galileo 1525 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• End gated 15cm wide x 25cm long ExpressCast™ UV-transparent gel tray with built-in fluorescent ruler and 14 comb slots.
• Two 1.5mm x 17 tooth combs
• Two 1.5mm x 34 tooth combs

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Additional gel trays.
• A wide range of comb options.
• Gel loading guides. These guides fit into the comb slots of the gel tray, and have precision machined slots that provide accurate aligning of your multi-channel pipet during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

1325 Gel Unit

by Galileo bioscience

The Galileo 1325 unit is a medium capacity system with long run lengths for high resolution. The ExpressCast™ gel casting system makes gel pouring quick, easy and tape-less!

The 1325 is a medium capacity system. With a maximum run length of 25cm, the unit can provide high resolution of complex analytes. Or, fitted with maximum capacity combs in all of the tray’s 6 comb slots, the unit can handle up to 112 samples. The 2325 features the Galileo ExpressCast gel casting system for quick, tape-free gel casting and includes a built-in bubble level and leveling screws for convenient level adjustment. You may choose from a wide variety of comb options to customize your order.

System Features

The Galileo 1325 complete system includes these features:

• Heavy duty lower buffer chamber
• Interlock safety lid with attached leads
• End gated 13cm wide x 25cm long ExpressCast™ UV-transparent gel tray with built-in fluorescent ruler and 6 comb slots.
• One 1.5mm x 12 tooth combs
• One 1.5mm x 16 tooth combs
• One 1.5mm x 20 tooth combs

System accessories

Choose amoung these accessories to customize each system for your specific needs.

• Additional gel trays.
• A wide range of comb options.
• Gel loading guides. These guides fit into the comb slots of the gel tray, and have precision machined slots that provide accurate aligning of your multi-channel pipet during gel loading.

View the Galileo Bioscience electrophoresis and blotting system catalog

DSC-800 Single Cell Suspension Tissue Dissociator – Includes Heating! Process up to 8 samples at once! 

A smarter way to dissociate single-cell suspension from human/mouse/rat tissue.

RWD Life Science DSC-800 is designed to help you quickly prepare tissue into a single cell suspension with high cell viability or tissue homogenate, greatly increasing experimental repeatability. Independent 8 channels with automatic processing improve the efficiency of organization processing.

RWD Single-cell suspension dissociator uses tissue processing tubes, tissue dissociation kits, and built-in optimization programs for preparing high-activity single-cell suspension and tissue homogenate. The preparation of single-cell suspension with high cell viability can be completed within 15-30 minutes, which makes the experiments more reproducible. 8 independent operating channels and heating jackets can automate the processes and improve the efficiency of tissue processing. Heating jackets are included as standard for fully automated sample preparation.

Applications

• Compound toxicity evaluation
• Drug development process
• Single-cell sequencing
• Primary cell culture
• Fluorescence-activated cell sorting
• Cell therapy
• Flow cytometry

Download brochure here.

The DSC-800 is easy to you and its color touchscreen and user-friendly software provides one-touch to run preset processing programs or edit custom programs.  It has 8 independent working channels and each channel can run different programs simultaneously, and it can also be equipped with a heating jacket to achieve automatic sample preparation. Sable motor speed ranges from 0 to 4000 rpm, capable of single-cell suspension and tissue homogenate. Customized tissue dissociation kits and tissue processing tubes can ensure cell viability and reduce experimental losses.

Specifications:

Download brochure: here

DSC-400 Single Cell Suspension Tissue Dissociator. Heating Included! Process up to 4 samples at once.

The smart way to to dissociate single-cell suspension from human/mouse/rat tissue.

The DSC-400 is designed to help you quickly prepare tissue into a single cell suspension with high cell viability or tissue homogenate, greatly increasing experimental repeatability. Independent four channels with automatic processing improve the efficiency of organization processing.

The DSC-400 single-cell suspension dissociator uses tissue processing tubes, tissue dissociation kits, and built-in optimization programs for preparing high-activity single-cell suspension and tissue homogenate. The preparation of single-cell suspension with high cell viability can be completed within 15-30 minutes, which makes the experiments more reproducible. 4 independent operating channels and heating jackets can automate the processes and improve the efficiency of tissue processing.

Heating jackets are available for fully automated sample preparation.

Applications

• Compound toxicity evaluation
• Drug development process
• Single-cell sequencing
• Primary cell culture
• Fluorescence-activated cell sorting
• Cell therapy
• Flow cytometry

Tissue processing tube specifications:

• Ethylene oxide(EO) sterilized
• Independent packaging makes it convenient for storage and use

The DSC-400 is easy to you and its color touchscreen and user-friendly software provides one-touch to run preset processing programs or edit custom programs.  It has 4 independent working channels and each channel can run different programs simultaneously, and it can also be equipped with a heating jacket to achieve automatic sample preparation. Sable motor speed ranges from 0 to 4000 rpm, capable of single-cell suspension and tissue homogenate. Customized tissue dissociation kits and tissue processing tubes can ensure cell viability and reduce experimental losses.

Specifications:

Download brochure: here

ULTRASENSITIVE, RELIABLE AND ACCURATE LUMINESCENCE MEASUREMENT

The Centro is a high-performance, easy-to-use and versatile microplate luminometer for both, glow and flash luminescence assays. The optimized optical system of the instrument provides lowest background and negligible crosstalk (10^-6). It can be equipped with up to 3 injectors.

The Centro XS version of the system has been built on the basis of the successful Centro, and shares with it its reliability and robustness, but has been optimized to increase its sensitivity even further: the Centro XS is the most sensitive microplate luminometer available and reliably measures less than 1.8 amol ATP per well. This makes the Centro XS the ideal partner for applications such as determination of cell viability, e.g. in tumour chemosensitivity assay, cell proliferation, antibiotic susceptibility testing or pathogen detection.

The Centro supports all basic luminescence technologies including:

• Flash-type Luminescence
• Glow-type Luminescence
• Cellular Luminescence
• Bio-Luminescence
• Chemi-Luminescence

Sensitive and reliable

Thanks to a stringent selection of photomultipliers working in photon counting mode and more than 40 years of experience building luminometers, the Centro provides highly sensitive luminescence detection: less than 5 amol ATP/well (25 fM) can be detected reliably. In the Centro XS, optics have been optimized to increase its sensitivity even further: below 1.8 amol ATP/well (9 fM).

Powerful crosstalk control – reliable results

Do you often see a few high-intensity samples surrounded by wells of low-intensity when running your samples?  Then you´re potentially affected by a phenomenon called crosstalk, that can produce wrong results and, hence, wrong conclusions. The crosstalk reduction design of the Centro does almost eliminate this problem: with a crosstalk of 10^-6, you never have to worry about the position of your high-intensity samples in your plate.

Integrated waste pump

Thanks to its built-in waste pump, you don’t need to worry about loading microplates, waste containers or removal of injector tips for washing and filling the reagent lines; the built-in waste pump takes care of the safe removal of excess liquids.

JET injectors: highest accuracy, speed and cell-friendliness

The Centro can be equipped with up to 3 JET injectors with variable volumes in pre-measurement or measurement position*. The ultra-fast injection speed of JET injectors eliminates any delay between injection and measurement and enables measurement of fast reactions, e.g. flash luminescence.

Berthold Technologies’ JET injectors use Teflon bellows for accurate and fast injections and guarantee most efficient mixing as well as extreme longevity.

• Accurate pipetting of small volumina: JET injectors ensure the injection of large and small volumes with high accuracy and offer a precision of more than 98% over the entire volume range
• Low maintenance costs: frictionless operation for extended lifetime
• Cell-friendly performance: cell-friendly materials and negligible shear forces enable worry-free injection of cell suspensions, e.g. in Aequorin-based calcium assays

* All injectors in pre-measurement position in the Centro XS.

Convenient Software options

Our microplate readers are powered by LightCompass®, a flexible software enabling easy data acquisition, analysis and reporting using Berthold Technologies’ instruments. It has been optimized for different microplate and tube formats. LightCompass® features all the functions you can expect from an advanced scientific software, such as flexible creation of measurement protocols, curve fitting, qualitative analysis and compliance with FDA 21 CFR Part 11.

LightCompass® is available in 3 different versions: Basic, Plus and Professional. Just pick the version that better suits your research needs.

TECHNICAL DETAILS

Detectors: Low-noise photomultiplier tube in single photon counting mode
Detection technologies: Luminescence
Measurement modes: Endpoint, Kinetics, Repeated, Area scan (up to 100 x 100 points per well)
Spectral range luminescence: 340-630 nm
Injectors: Up to 3 JET injectors with frictionless operation
Injector volume: 10-100 µL in 1 µL steps
Injector precision: Better than 2% across the entire volume range
Injector accuracy: Better than 2% across the entire volume range
Microplate formats: 96- and 384-well*  *Centro  XS only
Shaking: From ambient +5° to 45° C (not available in Centro XS)
Temperature control: From ambient +5° to 45° C (not available in Centro XS)
Luminescence sensitivity: Centro: <5 amol (25 fM) ATP/well (96-well plate)/Centro XS: <1.8 amol (9 fM) ATP/well (96-well plate)
Crosstalk: 10^-6
Dynamic range: >6 orders of magnitude
Interface: Windows software, connected to computer via USB
Operating system: Windows 10
Available software packages: LightCompass®: flexible software for data acquisition, analysis and reporting.
Regulations: CE, NRTL
Power Supply: 100 – 240 VAC ±10%, 50/60 Hz
Operating Voltage: 24 VDC / 6.67 A
Temperature tolerance: Storage: 0-40° C, Operation: 15-35° C
Humidity tolerance: 10-80% non-condensing, decreasing linearly to 50 %, relative humidity up to 40 °C, decreasing linearly to 50 %, relative humidity up to 40 °C
Dimensions (W x D x H): 334 x 437 x 287 mm
Weight: 21.8 kg

CELENA® S Digital Imaging System

Multicolor fluorescence imaging to data analysis in one device

The CELENA® S Digital Imaging System makes capturing high resolution, publication-quality images a breeze. Don’t let its size fool you, the CELENA® S is equipped with advanced precision optics, a highly sensitive CMOS sensor, digitally controlled LED light sources with hard-coated fluorescence filters, and a computer with image analysis software. The sophisticated yet simple software supports multicolor fluorescence imaging, brightfield imaging, phase contrast imaging, live cell time lapse imaging, and Z-stack imaging.

The All-In-One System for Exceptional Imaging Quality

VIBRANT, PUBLICATION-QUALITY IMAGES

Advanced precision optics and a highly sensitive camera allow you to capture high resolution, multi-channel fluorescence images.

LIVE CELL TIME LAPSE IMAGING

Live cells can be imaged in time lapse mode in a precisely controlled environment. The images can be used to create a video with annotations.

CELL COUNTING

Check cell concentration and viability in cell counter mode. The CELENA® S automatically adjusts light and focus for optimal results.

INTERCHANGEABLE FILTER CUBES AND OBJECTIVES

12+ hard-coated LED fluorescence filters. Infinity-corrected objectives with a magnification range of 1.25-100X

LIVE CELL IMAGING MADE SIMPLE WITH AN ONSTAGE INCUBATOR

The CELENA® S onstage incubation system can be set up for a variety of live cell imaging experiments in physiological and non-physiological conditions. The gas mixer allows precise control over the composition, humidity, and temperature of the air. The temperature controller heats the plate and lid of the stage incubator separately, for increased control over the temperature of the system as well as preventing condensation formation.

The CELENA® S makes it easy to set up a time lapse imaging sequence for lengthy cell-based assays, as well as exporting images or creating time-lapse videos complete with annotations.

A collection of vessel holders are available to accommodate various flasks, dishes, plates, and slides.

Download vessel holder selection guide

Objective Selection Guide

Our objectives provide excellent resolution, high contrast imaging, and color correction.

Download lens objective selection guide

LED Filter Cube Selection Guide

Download our LED filter cube selection guide to find which filter cubes fit your needs the best.

Download LED filter cube selection guide

How to use the CELENA-S

Capturing perfect images

Image analysis

Parfocal correction

Focus memory and fine AF

Z-stack imaging

Focus stacking images

Automated high content image acquisition and analysis for drug discovery and cell biology

 The CELENA® X High Content Imaging System is an integrated imaging system designed for rapid, high content image acquisition and analysis. Customizable imaging protocols, image-based and laser autofocusing modules, and a motorized XYZ stage simplify well plate imaging and slide scanning. The integrated CELENA® X Cell Analyzer software processes images and data for quantitative analysis. Analysis pipelines can be put together and reused to identify cellular or subcellular objects, process images for optimal data collection, and make various measurements. The CELENA® X is as flexible as it is powerful, with interchangeable objectives and filter cubes to accommodate a wide range of fixed and live cell imaging applications.

Laser Autofocus
Rapid and reproducible focusing
Minimized phototoxicity and photobleaching

Powerful, Easy-To-Use User Interface
Simple setup of imaging protocols
Seamless integration of imaging and data analysis processesCustomizable High Content Analysis

Imaging
Raw images
Metadata

Image Analysis
Morphology of individual cells and organelles
Spatial distribution of targets
Multiple measurements per cell
Differentiation of multiple phenotypes