New England BioGroup » Products » Instruments » FlowStar² Detector for Radio HPLC|Radio HPLC Detector
FlowStar² Detector for Radio HPLC|Radio HPLC Detector

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FlowStar² Detector for Radio HPLC|Radio HPLC Detector

Maximum Flexibility, Outstanding Sensitivity

In the FlowStar² LB 514 ultimate sensitivity has been combined with touch-screen technology for quick and easy operation. Designed for maximum ease of use, safety and flexibility, the FlowStar² LB 514 sets the new standard for what a radio-HPLC flow detector should be. With over 50 years of experience Berthold Technologies is taking radio-HPLC flow detection to the next level. A wide range of available cells ensures optimal performance and supports full compatibility with both, routine and challenging applications. The convenient dual mode capability enables simple installation in different configurations and makes integration into existing systems easy.

User friendly

The FlowStar² LB 514 is designed to be intuitive and easy to use, to get you up and running quickly. The intuitive touch screen interface makes it easy to get started and keep going. Results are displayed in both, a graphical chromatogram and a numerical format, so you can start interpreting your results in real time while the run is still in progress.Flowstar

The FlowStar² frees you from configuring parameters manually, thanks to the use of SmartCells: all measuring cells are equipped with a chip to automatically set the correct cell-specific system parameters. In addition, the software includes an extensive isotope library with predefined energy windows and cell usage options (14C, 3H, 32P, 33P, 35S, 128I, 111In, 99mTc…).

Easy integration into your HPLC system

Flowstar2-2The FlowStar² LB 514 makes integration easy so that everything works together to ensure consistent and reliable results. The integrated A/D converter records signals from external instruments (e.g. UV-detector) without requiring expensive additional hardware, while the USB port enables external control using RadioStar or other HPLC control software (e.g. Chromeleon™).

In addition, the dual analog output allows for the convenient integration into existing HPLC data systems.

The FlowStar² supports UHPLC and other LC technologies:

  • HPLC-MS (Mass Spectrometry)
  • HPLC-NMR (Nuclear Magnetic Resonance)

Safe and secure

The FlowStar² LB 514 embodies our commitment to providing everything you need for safe and easy integration into your lab environment.

Safety features:

  • Automatic HV shutdown for system
  • Built-in leak detection to prevent the measuring system from damage caused by aggressive liquids. The system will shut down automatically in the event of cell leakage.

Security features:

  • On-board system performance tests with instrument-based history function.
  • Password-based multi user access control to protect instrument from unauthorised use.


Several test cells are available to perform periodic system performance tests. These cells have been developed to meet GLP/GMP requirements and to guarantee a continuous system performance. Contact us for more information.

High sensitivity

The FlowStar² is the ultimate platform for high-sensitivity radio-HPLC flow detection. It uses random coincidence counting and luminescence subtraction for ultimate performance. In addition, the integrated spectrum scanning feature provides improved optimization of detector setup for each isotope.

Easy-to-use software for maximum productivity

The RadioStar software combines the ability to run sophisticated measurements with a user-friendly operation and user interface. In addition, a Chromeleon™ driver is available. Chromeleon™ is known as a very versatile chromatograpy software package supporting many different hardware solutions. The driver is fully certified, digitally signed by Thermo Scientific™ and runs with versions 6.x and 7.x

Measuring cells specific to your needs

Choose from a wide range of available SmartCells to meet your application needs. These high sensitivity cells are equipped with a SmartChip to automatically set the correct cell-specific system parameters. The automatic shut-down feature of the system after removal of a cell from the detector provides additional safety.flow cells

The range of SmartCells include:

  • Liquid scintillation (admixture) cells
  • Solid scintillator cells
  • Gamma isotopes and Positron Emitter (PET) cells
  • Cells for preparative SFC
  • Microbore cells for UHPLC and UPLC™
  • Special Iodine Cells (125I)
  • Cherenkov cells for high energy beta emitters


Detection unit: State-of-the-art ultrasensitive dual 2“ PMT detection system with random coincidence counting and luminescence subtraction.
Display: Graphical touch screen with 320 x 240 pixel resolution.
Interface: USB port (B-type), RS-232 for pump control
Inputs: Start-, Stop- and Ready signal (TTL). 2 analog inputs (24 bit resolution), variable voltage (bipolar, max 2.5 V)
Outputs: Scintillator pump control (RS-232 and analog). 2 analog signal outputs 0-1 V (2,5 times oversampling) with 16-bit resolution. Waste valve and fraction collector control output (open collector output).
Power Supply: 90-264 V, 50/60 Hz
Dimensions (W x D x H): 410 x 170 x 410 mm. Horizontal and vertical operation possible.
Weight: 16kg
Operating Temperature: 10-35°C
Storage Temperature: 5-40°C
Humidity: 10-90% (non condensing)

Software: The following possibilities are available:

  • Built-in software operated with touch screen
  • External control and evaluation via RadioStar software
  • External control and evaluation via Chromeleon™ driver.



New England BioGroup

PO Box 1231 Atkinson,
NH 03811-1231.
Toll Free USA: 800-779-1016
Main: 617-286-4632
Fax: 617-344-0055
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